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Levaquin is generally well tolerated however skin rashes, nausea, and stomach pain. Levaquin is a quinolone antibiotic and these antibiotics seem to be involved in joint problems, specifically tendinitis, thus people at increased risk for this type of problem should be closely monitored. This medication should be use only by people for whom it has been prescribed. Levofloxacin is a synthetic chemotherapeutic agent used to treat pneumonia and bronchitis. Levofloxacin is a synthetic chemotherapeutic agent used to treat pneumonia and bronchitis. Given with theophylline, Levofloxacin can increase theophylline blood levels.